Anti-CDC37 antibody [R01-8J-3] (STJA0033121)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenPeptide
STJA0033121
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General Information

Short DescriptionMouse monoclonal anti-CDC37 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostMouse
ReactivityHuman/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR01-8J-3
IsotypeIgG1k
ConjugationUnconjugated
PurificationProtein G
Dilution RangeWB 1:500-1:1000
FormulationLiquid in PBS, Glycerol and BSA
Storage InstructionStore at-20°C. Avoid freeze/thaw cycles.

Target Information

Gene SymbolCDC37
Gene ID11140
Uniprot IDCDC37_HUMAN
ImmunogenPeptide

Additional Info

Post Translational Modifications Constitutively sumoylated by UBE2I.
Function Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity.
Protein Name Hsp90 Co-Chaperone Cdc37
Hsp90 Chaperone Protein Kinase-Targeting Subunit
P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed
Database Links Reactome: R-HSA-1227986
Reactome: R-HSA-1236382
Reactome: R-HSA-5637810
Reactome: R-HSA-5675482
Reactome: R-HSA-8863795
Reactome: R-HSA-9013418
Reactome: R-HSA-9634285
Reactome: R-HSA-9652282
Reactome: R-HSA-9664565
Reactome: R-HSA-9665233
Reactome: R-HSA-9665244
Reactome: R-HSA-9665245
Reactome: R-HSA-9665246
Reactome: R-HSA-9665247
Reactome: R-HSA-9665249
Reactome: R-HSA-9665250
Reactome: R-HSA-9665251
Reactome: R-HSA-9665348
Reactome: R-HSA-9665686
Reactome: R-HSA-9665737
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Hsp90 Co-Chaperone Cdc37 antibody
Anti-Hsp90 Chaperone Protein Kinase-Targeting Subunit antibody
Anti-P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed antibody
Anti-CDC37 antibody
Anti-CDC37A antibody

Information sourced from Uniprot.org

Citations

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