| Host: | Mouse |
| Applications: | ELISA/WB/ICC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CDC37 (1-378aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | AT3G7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-A affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDC37 |
| Gene ID: | 11140 |
| Uniprot ID: | CDC37_HUMAN |
| Immunogen Region: | 1-378aa |
| Accession Number: | NP_008996 |
| Immunogen: | Recombinant human CDC37 (1-378aa) purified from E. coli |
| Post Translational Modifications | Constitutively sumoylated by UBE2I. |
| Function | Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity. |
| Protein Name | Hsp90 Co-Chaperone Cdc37Hsp90 Chaperone Protein Kinase-Targeting SubunitP50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-1227986Reactome: R-HSA-1236382Reactome: R-HSA-5637810Reactome: R-HSA-5675482Reactome: R-HSA-8863795Reactome: R-HSA-9013418Reactome: R-HSA-9634285Reactome: R-HSA-9652282Reactome: R-HSA-9664565Reactome: R-HSA-9665233Reactome: R-HSA-9665244Reactome: R-HSA-9665245Reactome: R-HSA-9665246Reactome: R-HSA-9665247Reactome: R-HSA-9665249Reactome: R-HSA-9665250Reactome: R-HSA-9665251Reactome: R-HSA-9665348Reactome: R-HSA-9665686Reactome: R-HSA-9665737 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Hsp90 Co-Chaperone Cdc37 antibodyAnti-Hsp90 Chaperone Protein Kinase-Targeting Subunit antibodyAnti-P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed antibodyAnti-CDC37 antibodyAnti-CDC37A antibody |
Information sourced from Uniprot.org
