Anti-CDC25C antibody (183-232 aa) (STJ92166)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CDC25C at the amino acid range 183-232
General Information
| Short Description | Rabbit polyclonal anti-M-phase inducer phosphatase 3 (183-232 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDC25C |
| Gene ID | 995 |
| Uniprot ID | MPIP3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CDC25C at the amino acid range 183-232 |
| Immunogen Region | 183-232 aa |
| Specificity | Cdc25C Polyclonal Antibody detects endogenous levels of Cdc25C protein. |
Additional Info
| Function | Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity. |
| Protein Name | M-Phase Inducer Phosphatase 3Dual Specificity Phosphatase Cdc25c |
| Database Links | Reactome: R-HSA-156711Reactome: R-HSA-176187Reactome: R-HSA-5625740Reactome: R-HSA-6804114Reactome: R-HSA-6804115Reactome: R-HSA-69273Reactome: R-HSA-75035Reactome: R-HSA-8862803 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-M-Phase Inducer Phosphatase 3 antibodyAnti-Dual Specificity Phosphatase Cdc25c antibodyAnti-CDC25C antibody |
Information sourced from Uniprot.org