| Post Translational Modifications | Phosphorylated by PLK2, leading to ubiquitination and degradation by the proteasome. Ubiquitinated and degraded following phosphorylation by PLK2. Phosphorylated by SRC and LCK. Phosphorylation by LCK increases its capacity to stimulate the GDP/GTP exchange on Ras, whereas its phosphorylation by SRC seems not to have an effect on stimulation activity. |
| Function | Promotes the exchange of Ras-bound GDP by GTP. |
| Protein Name | Ras-Specific Guanine Nucleotide-Releasing Factor 1Ras-Grf1Guanine Nucleotide-Releasing ProteinGnrpRas-Specific Nucleotide Exchange Factor Cdc25 |
| Database Links | Reactome: R-HSA-442982Reactome: R-HSA-5673001 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ras-Specific Guanine Nucleotide-Releasing Factor 1 antibodyAnti-Ras-Grf1 antibodyAnti-Guanine Nucleotide-Releasing Protein antibodyAnti-Gnrp antibodyAnti-Ras-Specific Nucleotide Exchange Factor Cdc25 antibodyAnti-RASGRF1 antibodyAnti-CDC25 antibodyAnti-GNRP antibodyAnti-GRF1 antibody |
Information sourced from Uniprot.org
