• Anti-CD97 antibody [MEM-180] (STJ16100121)

Anti-CD97 antibody [MEM-180] (STJ16100121)

SKU:
STJ16100121-01

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Host: Mouse
Applications: FC/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD97 is suitable for use in Flow Cytometry and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: MEM-180
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: ADGRE5
Gene ID: 976
Uniprot ID: AGRE5_HUMAN
Immunogen: PHA-activated peripheral blood cells
Tissue Specificity Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid.
Post Translational Modifications Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
Function Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
Protein Name Adhesion G Protein-Coupled Receptor E5
Leukocyte Antigen Cd97
Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta
Database Links Reactome: R-HSA-373080
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Adhesion G Protein-Coupled Receptor E5 Subunit Alpha: Secreted
Extracellular Space
Alternative Antibody Names Anti-Adhesion G Protein-Coupled Receptor E5 antibody
Anti-Leukocyte Antigen Cd97 antibody
Anti-Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta antibody
Anti-ADGRE5 antibody
Anti-CD97 antibody

Information sourced from Uniprot.org

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