| Short Description : | Goat polyclonal antibody anti-CD96 (C-Term) is suitable for use in ELISA research applications. |
| Applications: | Pep-ELISA |
| Host: | Goat |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments gave an approx 100+75kDa bands in Jurkat lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature f |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CD96 |
| Gene ID: | 10225 |
| Uniprot ID: | TACT_HUMAN |
| Accession Number: | NP_937839.1; NP_005807.1 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | KYTCIQEPNESD |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_937839.1; NP_005807.1). |
| Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
| Protein Name | T-Cell Surface Protein TactileCell Surface Antigen Cd96T Cell-Activated Increased Late Expression ProteinCd Antigen Cd96 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Surface Protein Tactile antibodyAnti-Cell Surface Antigen Cd96 antibodyAnti-T Cell-Activated Increased Late Expression Protein antibodyAnti-Cd Antigen Cd96 antibodyAnti-CD96 antibody |
Information sourced from Uniprot.org