Anti-CD89 antibody [R02-3E5] (STJA0036941)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CD89
General Information
| Short Description | Rabbit monoclonal anti-CD89 for use in WB, IHC-P, ICC, IF, IP and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/IP/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-3E5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:50FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | FCAR |
| Gene ID | 2204 |
| Uniprot ID | FCAR_HUMAN |
| Immunogen | A synthesized peptide derived from human CD89 |
Additional Info
| Tissue Specificity | Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages.however only one isoform is expressed at alveolar macrophages surfaces. |
| Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. |
| Protein Name | Immunoglobulin Alpha Fc ReceptorIga Fc ReceptorCd Antigen Cd89 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform A1: Cell MembraneSingle-Pass Type I Membrane Protein2: Cell Membrane3: Cell MembraneIsoform B: SecretedIsoform B-Delta-S2: Secreted |
| Alternative Antibody Names | Anti-Immunoglobulin Alpha Fc Receptor antibodyAnti-Iga Fc Receptor antibodyAnti-Cd Antigen Cd89 antibodyAnti-FCAR antibodyAnti-CD89 antibody |
Information sourced from Uniprot.org