Anti-CD85a/LILRB3 nanobody [SAA2289] (STJN000679)

SKU:
STJN000679
€234.60 - €1,583.40
Free Shipping
Processing The item has been added

Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-CD85a/LILRB3 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA2289
Conjugation: Unconjugated
Isotype: VHH-His
Formulation: PBS pH 7.4
Purification: Purified by Nickel column.
Concentration: Lot specific
Dilution Range: ELISA: 1:2000-1:20000
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact with the lab for this information.
Gene Symbol: LILRB3Uniprot ID=LIRB3_HUMAN"
Post Translational Modifications Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2.
Function May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3
Lir-3
Leukocyte Immunoglobulin-Like Receptor 3
Cd85 Antigen-Like Family Member A
Immunoglobulin-Like Transcript 5
Ilt-5
Monocyte Inhibitory Receptor Hl9
Cd Antigen Cd85a
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Nanobody Names Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 nanobody
Anti-Lir-3 nanobody
Anti-Leukocyte Immunoglobulin-Like Receptor 3 nanobody
Anti-Cd85 Antigen-Like Family Member A nanobody
Anti-Immunoglobulin-Like Transcript 5 nanobody
Anti-Ilt-5 nanobody
Anti-Monocyte Inhibitory Receptor Hl9 nanobody
Anti-Cd Antigen Cd85a nanobody
Anti-LILRB3 nanobody
Anti-ILT5 nanobody
Anti-LIR3 nanobody

Information sourced from Uniprot.org