| Post Translational Modifications | Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2. |
| Function | May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). |
| Protein Name | Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3Lir-3Leukocyte Immunoglobulin-Like Receptor 3Cd85 Antigen-Like Family Member AImmunoglobulin-Like Transcript 5Ilt-5Monocyte Inhibitory Receptor Hl9Cd Antigen Cd85a |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Nanobody Names | Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 nanobodyAnti-Lir-3 nanobodyAnti-Leukocyte Immunoglobulin-Like Receptor 3 nanobodyAnti-Cd85 Antigen-Like Family Member A nanobodyAnti-Immunoglobulin-Like Transcript 5 nanobodyAnti-Ilt-5 nanobodyAnti-Monocyte Inhibitory Receptor Hl9 nanobodyAnti-Cd Antigen Cd85a nanobodyAnti-LILRB3 nanobodyAnti-ILT5 nanobodyAnti-LIR3 nanobody |
Information sourced from Uniprot.org