Anti-CD80 antibody [C80-99] (STJ16101125)

SKU:
STJ16101125

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Host: Mouse
Applications: FC/IF/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD80 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: C80-99
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 min at RT; for staining of formalin-fixed tissues no suitable antigen retrieval method is known to date).
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: CD80
Gene ID: 941
Uniprot ID: CD80_HUMAN
Immunogen: A BALB/c mouse was immunized with recombinant full length CD80. Fusion partner: NS-1.
Tissue Specificity Expressed on activated B-cells, macrophages and dendritic cells.
Function Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Protein Name T-Lymphocyte Activation Antigen Cd80
Activation B7-1 Antigen
Bb1
Ctla-4 Counter-Receptor B7.1
B7
Cd Antigen Cd80
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-389356
Reactome: R-HSA-389357
Reactome: R-HSA-389359
Reactome: R-HSA-389513
Reactome: R-HSA-6783783
Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-T-Lymphocyte Activation Antigen Cd80 antibody
Anti-Activation B7-1 Antigen antibody
Anti-Bb1 antibody
Anti-Ctla-4 Counter-Receptor B7.1 antibody
Anti-B7 antibody
Anti-Cd Antigen Cd80 antibody
Anti-CD80 antibody
Anti-CD28LG antibody
Anti-CD28LG1 antibody
Anti-LAB7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance