Anti-CD8 antibody [C8/144B] (STJ16100344)

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STJ16100344
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-CD8 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : C8/144B
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Dilution Range: IHC 1: 25 – 1:100
Storage Instruction: Store at 2-8°C for up to 1-year, upon receipt.
Background The CD8 (cluster of differentiation 8) antigen is a cell surface glycoprotein made up of two subunits alpha and beta.1 Anti-CD8 is a T-cell marker for the detection of cytotoxic/suppressor lymphocytes. CD8 is also detected on NK cells, some thymocytes, some null cells and bone marrow cells. This antibody, along with other markers, can be used to distinguish between reactive and neoplastic Tcells.3 CD8 expression has been found to be negative in Mycosis Fungoides. Rarely does anti-CD8 label non-hematolymphoid neoplasms.

Information sourced from Uniprot.org