| Host: | Mouse |
| Applications: | WB/IHC-F/IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CD8 for use in WB, IHC-F and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 4B11 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | PBS with 0.09% sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Synthetic peptide derived from the carboxy terminal region of the human CD8 alpha chain coupled to a N-terminal cysteine, with the sequence C-KSDGKPSLSARYV. The peptide was coupled to bovine serum albumin and keyhole limpet hemocyanin. |
| Background | Mouse anti Human CD8 antibody, clone 4B11 recognizes the human CD8 cell surface antigen, a ~32 kDa glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. Mouse anti Human CD8 antibody, clone 4B11 was raised based on an earlier successful strategy used to generate rabbit polyclonal antibodies against human CD8 employing the same immunizing peptide (Mason et al. 1992).Mouse anti Human CD8 antibody, clone 4B11 has been reported as being suitable for use in Western blotting (Williamson et al. 1998). |
Information sourced from Uniprot.org
![Anti-CD8 antibody [4B11] (STJ16101716)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/152222/347074/STJ16101716_1__77855.1681999335.jpg?c=1 "Anti-CD8 antibody [4B11] (STJ16101716)")
