• Western blot analysis of lysate from MCF7 cells, using CD79B Antibody.
  • Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-lymph, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-lymph, antibody was diluted at 1:100
  • Western blot analysis of MCF7, L929, K562 cells using CD79b Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-CD79B antibody (61-110 aa) (STJ96620)

SKU:
STJ96620

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-B-cell antigen receptor complex-associated protein beta chain (61-110 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD79B
Gene ID: 974
Uniprot ID: CD79B_HUMAN
Immunogen Region: 61-110 aa
Specificity: CD79b Polyclonal Antibody detects endogenous levels of CD79b protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD79B at the amino acid range 61-110
Post Translational Modifications Phosphorylated on tyrosine upon B-cell activation by SRC-type Tyr-kinases such as BLK, LYN and SYK.
Function Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Protein Name B-Cell Antigen Receptor Complex-Associated Protein Beta Chain
B-Cell-Specific Glycoprotein B29
Ig-Beta
Immunoglobulin-Associated B29 Protein
Cd Antigen Cd79b
Database Links Reactome: R-HSA-5690714
Reactome: R-HSA-9679191
Reactome: R-HSA-983695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Following Antigen Binding
The Bcr Has Been Shown To Translocate From Detergent-Soluble Regions Of The Cell Membrane To Lipid Rafts Although Signal Transduction Through The Complex Can Also Occur Outside Lipid Rafts
Alternative Antibody Names Anti-B-Cell Antigen Receptor Complex-Associated Protein Beta Chain antibody
Anti-B-Cell-Specific Glycoprotein B29 antibody
Anti-Ig-Beta antibody
Anti-Immunoglobulin-Associated B29 Protein antibody
Anti-Cd Antigen Cd79b antibody
Anti-CD79B antibody
Anti-B29 antibody
Anti-IGB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance