Anti-CD70 antibody [Ki-24] (STJ16103312)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG3k
Immunogenhuman L428 cell line
General Information
| Short Description | Mouse monoclonal anti-CD70 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | Ki-24 |
| Isotype | IgG3k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by protein-A affinity chromatography. |
| Formulation | Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | CD70 |
| Gene ID | 970 |
| Uniprot ID | CD70_HUMAN |
| Immunogen | human L428 cell line |
Additional Info
| Function | Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. |
| Protein Name | Cd70 AntigenCd27 LigandCd27-LTumor Necrosis Factor Ligand Superfamily Member 7Cd Antigen Cd70 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Cd70 Antigen antibodyAnti-Cd27 Ligand antibodyAnti-Cd27-L antibodyAnti-Tumor Necrosis Factor Ligand Superfamily Member 7 antibodyAnti-Cd Antigen Cd70 antibodyAnti-CD70 antibodyAnti-CD27L antibodyAnti-CD27LG antibodyAnti-TNFSF7 antibody |
Information sourced from Uniprot.org