| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CD7 (132-146) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 37kDa band observed in Human Thymus lysates (calculated MW of 25.4kDa according to NP_006128.1). We do note that CD7 is a glycoprotein which makes a higher size band to be expec |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CD7 |
| Gene ID: | 924 |
| Uniprot ID: | CD7_HUMAN |
| Immunogen Region: | 132-146 |
| Accession Number: | NP_006128.1 |
| Specificity: | The immunizing peptide corresponds to a part of the extracellular domain. |
| Immunogen Sequence: | TEEQSQGWHRCSDAP |
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. |
| Protein Name | T-Cell Antigen Cd7Gp40T-Cell Leukemia AntigenT-Cell Surface Antigen Leu-9Tp41Cd Antigen Cd7 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell Antigen Cd7 antibodyAnti-Gp40 antibodyAnti-T-Cell Leukemia Antigen antibodyAnti-T-Cell Surface Antigen Leu-9 antibodyAnti-Tp41 antibodyAnti-Cd Antigen Cd7 antibodyAnti-CD7 antibody |
Information sourced from Uniprot.org
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