Anti-CD66c/CEACAM6 nanobody [SAA1208] (STJN000214)

SKU:
STJN000214
£378.50 - £1,632.50
Free Shipping
Processing The item has been added

Host: Alpaca
Applications: ELISA/FC/IF/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Cell Adhesion Molecule Ceacam6 is suitable for use in ELISA, Flow Cytometry, Immunofluorescence and Western Blot research applications.
Clonality : Monoclonal
Clone ID : SAA1208
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: CEACAM6
Gene ID: 4680
Uniprot ID: CEAM6_HUMAN
Post Translational Modifications Glycosylated.
Function Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells.
Protein Name Cell Adhesion Molecule Ceacam6
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6
Cea Cell Adhesion Molecule 6
Non-Specific Crossreacting Antigen
Normal Cross-Reacting Antigen
Cd Antigen Cd66c
Database Links Reactome: R-HSA-1566977
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Nanobody Names Anti-Cell Adhesion Molecule Ceacam6 nanobody
Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 nanobody
Anti-Cea Cell Adhesion Molecule 6 nanobody
Anti-Non-Specific Crossreacting Antigen nanobody
Anti-Normal Cross-Reacting Antigen nanobody
Anti-Cd Antigen Cd66c nanobody
Anti-CEACAM6 nanobody
Anti-NCA nanobody

Information sourced from Uniprot.org