Anti-CD62E/E-Selectin antibody (22-230 aa) [SRM] (STJ11107318)

SKU:
STJ11107318

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Monoclonal
Clone ID: SRM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:4000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: SELE
Gene ID: 6401
Uniprot ID: LYAM2_HUMAN
Immunogen Region: 22-230 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human CD62E/E-Selectin (NP_000441.2).
Immunogen Sequence: WSYNTSTEAMTYDEASAYCQ QRYTHLVAIQNKEEIEYLNS ILSYSPSYYWIGIRKVNNVW VWVGTQKPLTEEAKNWAPGE PNNRQKDEDCVEIYIKREKD VGMWNDERCSKKKLALCYTA ACTNTSCSGHGECVETINNY TCKCDPGFSGLKCEQIVNCT ALESPEHGSLVCSHPLGNFS YNSSCSISCDRGYLPSSMET MQCMSSGEW
Function Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
Protein Name E-Selectin
Cd62 Antigen-Like Family Member E
Endothelial Leukocyte Adhesion Molecule 1
Elam-1
Leukocyte-Endothelial Cell Adhesion Molecule 2
Lecam2
Cd Antigen Cd62e
Database Links Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-E-Selectin antibody
Anti-Cd62 Antigen-Like Family Member E antibody
Anti-Endothelial Leukocyte Adhesion Molecule 1 antibody
Anti-Elam-1 antibody
Anti-Leukocyte-Endothelial Cell Adhesion Molecule 2 antibody
Anti-Lecam2 antibody
Anti-Cd Antigen Cd62e antibody
Anti-SELE antibody
Anti-ELAM1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance