| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Lymphocyte Function-Associated antigen 3 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | TS2/9.1 |
| Conjugation: | PE/TR |
| Isotype: | IgG1k |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Concentration: | 5 Mu L/Test |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Gene Symbol: | CD58 |
| Gene ID: | 965 |
| Uniprot ID: | LFA3_HUMAN |
| Function | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
| Protein Name | Lymphocyte Function-Associated Antigen 3 Ag3 Surface Glycoprotein Lfa-3 Cd Antigen Cd58 |
| Database Links | Reactome: R-HSA-202733 Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Lymphocyte Function-Associated Antigen 3 antibody Anti-Ag3 antibody Anti-Surface Glycoprotein Lfa-3 antibody Anti-Cd Antigen Cd58 antibody Anti-CD58 antibody Anti-LFA3 antibody |
Information sourced from Uniprot.org