| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC/FC |
| Reactivity: | Human/Rat/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CD56/NCAM1-Isoform 2 (Internal) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 150-170kDa band observed in Human Cerebellum and Frontal Cortex lysates (calculated MW of 94.6kDa according to NP_851996.2). The observed molecular weight corresponds to the gly |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | NCAM1 |
| Gene ID: | 4684 |
| Uniprot ID: | NCAM1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_851996.2 |
| Specificity: | This antibody is expected to recognize reported isoform 2 (NP_851996.2) only. |
| Immunogen Sequence: | KASWTRPEKQETLD |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus. |
| Protein Name | Neural Cell Adhesion Molecule 1N-Cam-1Ncam-1Cd Antigen Cd56 |
| Database Links | Reactome: R-HSA-3000178Reactome: R-HSA-375165Reactome: R-HSA-419037Reactome: R-HSA-445144Reactome: R-HSA-5673001Reactome: R-HSA-877300 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 3: Cell MembraneLipid-AnchorGpi-AnchorIsoform 4: Cell MembraneIsoform 5: SecretedIsoform 6: Secreted |
| Alternative Antibody Names | Anti-Neural Cell Adhesion Molecule 1 antibodyAnti-N-Cam-1 antibodyAnti-Ncam-1 antibodyAnti-Cd Antigen Cd56 antibodyAnti-NCAM1 antibodyAnti-NCAM antibody |
Information sourced from Uniprot.org
