| Host: |
Rat |
| Applications: |
FC |
| Reactivity: |
Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rat monoclonal antibody anti-Integrin alpha-2 is suitable for use in Flow Cytometry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
DX5 |
| Conjugation: |
AF488 |
| Isotype: |
IgMk |
| Formulation: |
PBS with 0.05% Proclin300, 1% BSA |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Function | Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis. |
| Protein Name | Integrin Alpha-2Cd49 Antigen-Like Family Member BCollagen ReceptorPlatelet Membrane Glycoprotein IaGpiaVla-2 Subunit AlphaCd Antigen Cd49b |
| Database Links | Reactome: R-MMU-216083Reactome: -MMU-3000170Reactome: -MMU-3000178Reactome: -MMU-8874081 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-2 antibodyAnti-Cd49 Antigen-Like Family Member B antibodyAnti-Collagen Receptor antibodyAnti-Platelet Membrane Glycoprotein Ia antibodyAnti-Gpia antibodyAnti-Vla-2 Subunit Alpha antibodyAnti-Cd Antigen Cd49b antibodyAnti-Itga2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000698) [Used at 0.02 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/145551/292209/STJA0000698_1__44991.1631206052.jpg?c=1 "Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000698) [Used at 0.02 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.")
![C57BL/6 murine splenocytes were stained with Anti-Mouse CD49b Monoclonal Antibody (AF647 Conjugated)[Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/145557/292215/STJA0000704_1__60020.1631206058.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-Mouse CD49b Monoclonal Antibody (AF647 Conjugated)[Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.")
![Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000699) [Used at 0.02 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/145552/292210/STJA0000699_1__59246.1631206053.jpg?c=1 "Mouse bone marrow cells were stained with Anti-CD49b antibody (STJA0000699) [Used at 0.02 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained bone marrow cells (blank black histogram) were used as control.")