| Host: | Mouse |
| Applications: | IHC-F/ELISA/FC/IF/IP/IHC-P/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD49b is suitable for use in Immunohistochemistry, ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 16B4 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS with <0.1% sodium azide |
| Purification: | Purified |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
| Immunogen: | Purified human beta 1 preparation from HT1080 fibrosarcoma cell extract |
| Background | Mouse anti Human CD49b antibody, clone 16B4 recognizes human CD49b, also known as integrin Alpha 2, collagen receptor, Platelet membrane glycoprotein Ia or VLA-2 subunit alpha. CD49b is a 1181 amino acid ~160 kDa single pass type-1 transmembrane glycoprotein possessing multiple FG-GAP repeats and a single VWFA domain. Mouse anti human CD49b antibody, clone 16B4 is identified as capable of immunoprecipitating a non-reducible alpha subunit from I125 surface labeled human cell line extract. It is confirmed as specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in dot blots |
Information sourced from Uniprot.org