Anti-CD45RB antibody [MEM-55] (STJ16100086)

Anti-CD45RB antibody [MEM-55] (STJ16100086)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenHuman thymocytes and T lymphocytes.
STJ16100086-01
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General Information

Short DescriptionMouse monoclonal anti-CD45RB for use in FC, IP, WB and IHC-P in Non-Human Primates and Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsFC/IP/WB/IHC-P
HostMouse
ReactivityNon-Human Primates/Human
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDMEM-55
IsotypeIgG1
ConjugationUnconjugated
Concentration1 mg/mL
FormulationPhosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenHuman thymocytes and T lymphocytes.

Additional Info

Background CD45RB is an of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed e.g. in microglia and inflammatory cells.

Information sourced from Uniprot.org

Citations

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