Anti-CD43 antibody [DFT-1] (STJ16101913)

SKU:
STJ16101913-02

£741.50
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Host: Mouse
Applications: IHC-F/FC/IF/IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD43 is suitable for use in Immunohistochemistry, Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: DFT-1
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS with <0.1% sodium azide
Purification: Purified
Concentration: 1 mg/mL
Storage Instruction: Store aliquots at-20°C, and thawed aliquots at 2-8°C.
Immunogen: KG-1 cells
Background Mouse anti Human CD43 antibody, clone DFT-1 recognizes human CD43 also known as leukosialin or sialophorin. CD43 is a 381 amino acid single pass type I transmembrane glycoprotein present on the cell surface of multiple cell types including thymocytes, T-lymphocytes, neutrophils, plasma cells and platelets. It is lacking on the surface of most B-lymphocytes. CD34 is a major membrane sialoglycoprotein expressed on T lymphocytes as two predominant glycoforms, a ~115 kDa form present on all T-cells and a ~130 kDa form indicative of T-cell activation (Barren et al. 1997) and acts as a T-cell counter-receptor for CD169/Siglec-1 (van den Berg et al. 2001). Mouse anti Human CD43 antibody, clone DFT-1 binds to both glycoforms of human CD43 (Kyoizumi et al. 2004)

Information sourced from Uniprot.org

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