| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
GP5 |
| Gene ID: |
2814 |
| Uniprot ID: |
GPV_HUMAN |
| Immunogen Region: |
17-477 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 17-477 of human CD42d (NP_004479.1). |
| Immunogen Sequence: |
QPFPCPPACKCVFRDAAQCS GGDVARISALGLPTNLTHIL LFGMGRGVLQSQSFSGMTVL QRLMISDSHISAVAPGTFSD LIKLKTLRLSRNKITHLPGA LLDKMVLLEQLFLDHNALRG IDQNMFQKLVNLQELALNQN QLDFLPASLFTNLENLKLLD LSGNNLTHLPKGLLGAQAKL ERLLLHSNRLVSLDSGLLNS LGALTELQFHRNHIRSIAPG AFDRLPNLSSLTLSRNHLA |
| Tissue Specificity | Platelets and megakaryocytes. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. |
| Protein Name | Platelet Glycoprotein VGpvGlycoprotein 5Cd Antigen Cd42d |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-9673221Reactome: R-HSA-9845620Reactome: R-HSA-9846298 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Platelet Glycoprotein V antibodyAnti-Gpv antibodyAnti-Glycoprotein 5 antibodyAnti-Cd Antigen Cd42d antibodyAnti-GP5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
