| Short Description : | Rabbit polyclonal CD42d (17-477 aa) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GP5 |
| Gene ID: | 2814 |
| Uniprot ID: | GPV_HUMAN |
| Immunogen Region: | 17-477 aa |
| Immunogen Sequence: | QPFPCPPACKCVFRDAAQCS GGDVARISALGLPTNLTHIL LFGMGRGVLQSQSFSGMTVL QRLMISDSHISAVAPGTFSD LIKLKTLRLSRNKITHLPGA LLDKMVLLEQLFLDHNALRG IDQNMFQKLVNLQELALNQN QLDFLPASLFTNLENLKLLD LSGNNLTHLPKGLLGAQAKL ERLLLHSNRLVSLDSGLLNS LGALTELQFHRNHIRSIAPG AFDRLPNLSSLTLSRNHLA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-477 of human CD42d (NP_004479.1). |
| Tissue Specificity | Platelets and megakaryocytes. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. |
| Protein Name | Platelet Glycoprotein VGpvGlycoprotein 5Cd Antigen Cd42d |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-9673221Reactome: R-HSA-9845620Reactome: R-HSA-9846298 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Platelet Glycoprotein V antibodyAnti-Gpv antibodyAnti-Glycoprotein 5 antibodyAnti-Cd Antigen Cd42d antibodyAnti-GP5 antibody |
Information sourced from Uniprot.org
