Anti-CD40 antibody [ZN183] (STJA0033353)

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STJA0033353
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-CD40 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : ZN183
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification: Affinity Chromatography
Concentration: 0.5-1.0 mg/mL
Dilution Range: IHC 1:50-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: CD40
Gene ID: 958
Uniprot ID: TNR5_HUMAN
Immunogen: Human recombinant protein fragment of human CD40 (NP_001241) produced in E.coli.
Tissue Specificity B-cells and in primary carcinomas.
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 5
B-Cell Surface Antigen Cd40
Bp50
Cd40l Receptor
Cdw40
Cd Antigen Cd40
Database Links Reactome: R-HSA-198933 P25942-1
Reactome: R-HSA-5668541 P25942-1
Reactome: R-HSA-5676594 P25942-1
Cellular Localisation Isoform I: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Ii: Secreted
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibody
Anti-B-Cell Surface Antigen Cd40 antibody
Anti-Bp50 antibody
Anti-Cd40l Receptor antibody
Anti-Cdw40 antibody
Anti-Cd Antigen Cd40 antibody
Anti-CD40 antibody
Anti-TNFRSF5 antibody

Information sourced from Uniprot.org

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