| Host: | Mouse |
| Applications: | IHC-P/FC/IHC-F/IP |
| Reactivity: | Human/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD40 is suitable for use in Immunohistochemistry, Flow Cytometry, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | LOB7/6 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | TBS |
| Concentration: | 1.0 mg/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Gene Symbol: | CD40 |
| Gene ID: | 958 |
| Uniprot ID: | TNR5_HUMAN |
| Immunogen: | CD40 Ig (Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG. |
| Tissue Specificity | B-cells and in primary carcinomas. |
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibodyAnti-B-Cell Surface Antigen Cd40 antibodyAnti-Bp50 antibodyAnti-Cd40l Receptor antibodyAnti-Cdw40 antibodyAnti-Cd Antigen Cd40 antibodyAnti-CD40 antibodyAnti-TNFRSF5 antibody |
Information sourced from Uniprot.org

