Host: |
Mouse |
Applications: |
IHC-P/FC/IHC-F/IP |
Reactivity: |
Human/Dog |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-CD40 is suitable for use in Immunohistochemistry, Flow Cytometry, Immunohistochemistry and Immunoprecipitation research applications. |
Clonality: |
Monoclonal |
Clone ID: |
LOB7/6 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2a |
Formulation: |
TBS |
Concentration: |
1.0 mg/mL |
Storage Instruction: |
Store at 2-8°C upon receipt. |
Gene Symbol: |
CD40 |
Gene ID: |
958 |
Uniprot ID: |
TNR5_HUMAN |
Immunogen: |
CD40 Ig (Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG. |
Tissue Specificity | B-cells and in primary carcinomas. |
Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibodyAnti-B-Cell Surface Antigen Cd40 antibodyAnti-Bp50 antibodyAnti-Cd40l Receptor antibodyAnti-Cdw40 antibodyAnti-Cd Antigen Cd40 antibodyAnti-CD40 antibodyAnti-TNFRSF5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance