| Host: |
Mouse |
| Applications: |
Stim/FA/FC |
| Reactivity: |
Human |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : |
Mouse monoclonal antibody anti-Tumor necrosis factor receptor superfamily member 5 is suitable for use in Universal, FA and Flow Cytometry research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
G28.5 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at 2-8°C. Do not freeze this product. |
| Tissue Specificity | B-cells and in primary carcinomas. |
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibodyAnti-B-Cell Surface Antigen Cd40 antibodyAnti-Bp50 antibodyAnti-Cd40l Receptor antibodyAnti-Cdw40 antibodyAnti-Cd Antigen Cd40 antibodyAnti-CD40 antibodyAnti-TNFRSF5 antibody |
Information sourced from Uniprot.org
