| Host: | Mouse |
| Applications: | Stim/FA/FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Tumor necrosis factor receptor superfamily member 5 is suitable for use in Universal, FA and Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | G28.5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | 0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at 2-8°C. Do not freeze this product. |
| Gene Symbol: | CD40 |
| Gene ID: | 958 |
| Uniprot ID: | TNR5_HUMAN |
| Tissue Specificity | B-cells and in primary carcinomas. |
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5 B-Cell Surface Antigen Cd40 Bp50 Cd40l Receptor Cdw40 Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1 Reactome: R-HSA-5668541 P25942-1 Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell Membrane Single-Pass Type I Membrane Protein Isoform Ii: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibody Anti-B-Cell Surface Antigen Cd40 antibody Anti-Bp50 antibody Anti-Cd40l Receptor antibody Anti-Cdw40 antibody Anti-Cd Antigen Cd40 antibody Anti-CD40 antibody Anti-TNFRSF5 antibody |
Information sourced from Uniprot.org