| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Ectonucleoside triphosphate diphosphohydrolase 1 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | A1 |
| Conjugation: | FITC |
| Isotype: | IgG1k |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Concentration: | 5 Mu L/Test |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Gene Symbol: | ENTPD1 |
| Gene ID: | 953 |
| Uniprot ID: | ENTP1_HUMAN |
| Tissue Specificity | Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Highly expressed in placenta, lung, skeletal muscle, kidney. |
| Post Translational Modifications | N-glycosylated. The N-terminus is blocked. Palmitoylated on Cys-13.which is required for caveola targeting. |
| Function | Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 1 Atp Diphosphohydrolase Atp-Dph Atpdase Ecto-Atp Diphosphohydrolase 1 Ecto-Atpdase 1 Ecto-Atpase 1 Ecto-Apyrase Lymphoid Cell Activation Antigen Nucleoside Triphosphate Diphosphohydrolase 1 Ntpdase1 Cd Antigen Cd39 |
| Database Links | Reactome: R-HSA-8850843 Reactome: R-HSA-9660826 |
| Cellular Localisation | Membrane Multi-Pass Membrane Protein Caveola |
| Alternative Antibody Names | Anti-Ectonucleoside Triphosphate Diphosphohydrolase 1 antibody Anti-Atp Diphosphohydrolase antibody Anti-Atp-Dph antibody Anti-Atpdase antibody Anti-Ecto-Atp Diphosphohydrolase 1 antibody Anti-Ecto-Atpdase 1 antibody Anti-Ecto-Atpase 1 antibody Anti-Ecto-Apyrase antibody Anti-Lymphoid Cell Activation Antigen antibody Anti-Nucleoside Triphosphate Diphosphohydrolase 1 antibody Anti-Ntpdase1 antibody Anti-Cd Antigen Cd39 antibody Anti-ENTPD1 antibody Anti-CD39 antibody |
Information sourced from Uniprot.org