• Western blot analysis of extracts of various cell lines, using CD38 antibody (STJ22994) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.
  • Immunohistochemistry of paraffin-embedded human lung cancer using CD38 rabbit polyclonal antibody (STJ22994) at dilution of 1:150 (40x lens).
  • Immunofluorescence analysis of THP-1 cells using CD38 antibody (STJ22994) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of mouse spleen using CD38 antibody (STJ22994) at dilution of 1:100. Blue: DAPI for nuclear staining.

Anti-CD38 antibody (181-300) (STJ22994)

SKU:
STJ22994

£169.50 - £449.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CD38 (181-300) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD38
Gene ID: 952
Uniprot ID: CD38_HUMAN
Immunogen Region: 181-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 181-300 of human CD38 (NP_001766.2).
Immunogen Sequence: SNNPVSVFWKTVSRRFAEAA CDVVHVMLNGSRSKIFDKNS TFGSVEVHNLQPEKVQTLEA WVIHGGREDSRDLCQDPTIK ELESIISKRNIQFSCKNIYR PDKFLQCVKNPEDSSCTSEI
Tissue Specificity Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Function Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity.
Protein Name Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1
2'-Phospho-Adp-Ribosyl Cyclase
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase
2'-Phospho-Cyclic-Adp-Ribose Transferase
Adp-Ribosyl Cyclase 1
Adprc 1
Cyclic Adp-Ribose Hydrolase 1
Cadpr Hydrolase 1
T10
Cd Antigen Cd38
Database Links Reactome: R-HSA-196807
Cellular Localisation Cell Surface
Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 antibody
Anti-2'-Phospho-Adp-Ribosyl Cyclase antibody
Anti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase antibody
Anti-2'-Phospho-Cyclic-Adp-Ribose Transferase antibody
Anti-Adp-Ribosyl Cyclase 1 antibody
Anti-Adprc 1 antibody
Anti-Cyclic Adp-Ribose Hydrolase 1 antibody
Anti-Cadpr Hydrolase 1 antibody
Anti-T10 antibody
Anti-Cd Antigen Cd38 antibody
Anti-CD38 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance