| Host: | Mouse |
| Applications: | IHC-F/FC/IHC-P/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-CD35 is suitable for use in Immunohistochemistry, Flow Cytometry, Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | E11 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS with <0.1% sodium azide |
| Purification: | Purified |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
| Immunogen: | Human acute monocytic leukaemia cells |
| Background | Mouse anti Human CD35 antibody, clone E11 recognizes complement receptor type 1, also known as CD35 or the C3b/C4b receptor. CD35 a single chain, type I single pass transmembrane glycoprotein which exists in four allotypic forms (A, B, C, D) of ~190 kDa, ~220 kDa, ~160 kDa and ~250 kDa respectively (Khera et al. 2009).CD35 is expressed by granulocytes, monocytes, B cells and some T cells. Functionally, CD35 acts as a receptor for the C3b component of complement. |
Information sourced from Uniprot.org