Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-CD34 is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S5019RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
Cd34 |
Gene ID: |
12490 |
Uniprot ID: |
CD34_MOUSE |
Immunogen: |
Recombinant protein of human CD34. |
Tissue Specificity | Expressed in the kidney where it is detected in the thin limb of Henle's loop (at protein level). Highly expressed in hematopoietic progenitor cell lines, brain and testis, and moderately in the thymus, spleen, and bone marrow, but not in adult liver. |
Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
Database Links | Reactome: R-MMU-198933 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-Cd34 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance