Anti-CD32b/FCGR2B nanobody [SAA1313] (STJN000199)

Anti-CD32b/FCGR2B nanobody [SAA1313] (STJN000199)

SKU:
STJN000199
£378.50 - £1,632.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1313
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: FCGR2B
Gene ID: 2213
Uniprot ID: FCG2B_HUMAN
Post Translational Modifications Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.
Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B
Igg Fc Receptor Ii-B
Cdw32
Fc-Gamma Rii-B
Fc-Gamma-Riib
Fcrii-B
Cd Antigen Cd32
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Nanobody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B nanobody
Anti-Igg Fc Receptor Ii-B nanobody
Anti-Cdw32 nanobody
Anti-Fc-Gamma Rii-B nanobody
Anti-Fc-Gamma-Riib nanobody
Anti-Fcrii-B nanobody
Anti-Cd Antigen Cd32 nanobody
Anti-FCGR2B nanobody
Anti-CD32 nanobody
Anti-FCG2 nanobody
Anti-IGFR2 nanobody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0027249 Anti-CD32b/FCGR2B antibody [SAA0547] (STJA0027249) Human Monoclonal Human ELISA/FC/IHC/WB
STJA0027248 Anti-CD32b/FCGR2B antibody [6G08] (STJA0027248) Mouse Monoclonal Human FC
STJA0031306 Anti-CD32b/FCGR2B antibody [6G08] {PE} (STJA0031306) Mouse Monoclonal Human FC
STJA0030339 Anti-CD32b/FCGR2B antibody [SAA0547] {PerCP} (STJA0030339) Human Monoclonal Human ELISA/FC/WB
STJA0029373 Anti-CD32b/FCGR2B antibody [SAA0547] {APC} (STJA0029373) Human Monoclonal Human ELISA/FC/WB
!