Anti-CD303/CLEC4C antibody [122A2] {FITC} (STJA0028670)

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STJA0028670
£254.50 - £378.50
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Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-C-Type Lectin Domain Family 4 Member C is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 122A2
Conjugation: FITC
Isotype: IgG1k
Formulation: 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Purification: Purified
Concentration: 0.5 mg/mL
Storage Instruction: Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol: CLEC4C
Gene ID: 170482
Uniprot ID: CLC4C_HUMAN
Function Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Protein Name C-Type Lectin Domain Family 4 Member C
Blood Dendritic Cell Antigen 2
Bdca-2
C-Type Lectin Superfamily Member 7
Dendritic Lectin
Cd Antigen Cd303
Database Links Reactome: R-HSA-5621480
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-C-Type Lectin Domain Family 4 Member C antibody
Anti-Blood Dendritic Cell Antigen 2 antibody
Anti-Bdca-2 antibody
Anti-C-Type Lectin Superfamily Member 7 antibody
Anti-Dendritic Lectin antibody
Anti-Cd Antigen Cd303 antibody
Anti-CLEC4C antibody
Anti-BDCA2 antibody
Anti-CLECSF11 antibody
Anti-CLECSF7 antibody
Anti-DLEC antibody
Anti-HECL antibody
Anti-UNQ9361 antibody
Anti-PRO34150 antibody

Information sourced from Uniprot.org