Anti-CD300a antibody [SRM14842] (STJ11109572)

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STJ11109572
€142.20 - €625.80
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Applications:WB/FC/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SRM14842
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity purification
Dilution Range:WB, 1:500-1:2000
FC, 1:1000-1:5000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CD300A
Gene ID:11314
Uniprot ID:CLM8_HUMAN
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
Post Translational Modifications Phosphorylated on tyrosine. N-glycosylated.
Function Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
Protein Name Cmrf35-Like Molecule 8
Clm-8
Cd300 Antigen-Like Family Member A
Cmrf-35-H9
Cmrf35-H9
Cmrf35-H
Irc1/Irc2
Immunoglobulin Superfamily Member 12
Igsf12
Inhibitory Receptor Protein 60
Irp60
Nk Inhibitory Receptor
Cd Antigen Cd300a
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Cmrf35-Like Molecule 8 antibody
Anti-Clm-8 antibody
Anti-Cd300 Antigen-Like Family Member A antibody
Anti-Cmrf-35-H9 antibody
Anti-Cmrf35-H9 antibody
Anti-Cmrf35-H antibody
Anti-Irc1/Irc2 antibody
Anti-Immunoglobulin Superfamily Member 12 antibody
Anti-Igsf12 antibody
Anti-Inhibitory Receptor Protein 60 antibody
Anti-Irp60 antibody
Anti-Nk Inhibitory Receptor antibody
Anti-Cd Antigen Cd300a antibody
Anti-CD300A antibody
Anti-CMRF35H antibody
Anti-IGSF12 antibody
Anti-HSPC083 antibody

Information sourced from Uniprot.org

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