| Host: |
Hamster |
| Applications: |
Activ/Block/FC/IHC/IP |
| Reactivity: |
Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Hamster monoclonal antibody anti-T-cell-specific surface glycoprotein CD28 is suitable for use in Universal, Universal, Flow Cytometry, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
37.51 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay. |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
Store at 2-8°C. Do not freeze this product. |
| Function | Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. |
| Protein Name | T-Cell-Specific Surface Glycoprotein Cd28Cd Antigen Cd28 |
| Database Links | Reactome: R-MMU-1257604Reactome: -MMU-389356Reactome: -MMU-389357Reactome: -MMU-389359Reactome: -MMU-6811558 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Cell-Specific Surface Glycoprotein Cd28 antibodyAnti-Cd Antigen Cd28 antibodyAnti-Cd28 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![C57BL/6 murine splenocytes were stained with Anti-Mouse CD28 Monoclonal Antibody (AF647 Conjuaged)[Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated). Splenocytes stained with Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated) (right) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/145129/291795/STJA0000276_1__56941.1631205595.jpg?c=1 "C57BL/6 murine splenocytes were stained with Anti-Mouse CD28 Monoclonal Antibody (AF647 Conjuaged)[Used at 0.2 µg/10<sup>6</sup> cells dilution] and Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated). Splenocytes stained with Anti-Mouse CD3 Monoclonal Antibody (AF488 Conjugated) (right) were used as control.")