Anti-CD273/PDCD1LG2 antibody [24F.10C12] {APC} (STJA0001965)

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STJA0001965
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Short Description :Mouse monoclonal anti-Programmed cell death 1 ligand 2 for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Mouse
Reactivity:Human
Note:FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Clonality :Monoclonal
Clone ID :24F.10C12
Isotype:IgG2ak
Conjugation:APC
Concentration:5 Mu L/Test
Formulation:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instruction:Store between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol:PDCD1LG2
Gene ID:80380
Uniprot ID:PD1L2_HUMAN
Tissue Specificity Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-HSA-389948
Cellular Localisation Isoform 3: Secreted
Isoform 2: Endomembrane System
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Alternative Antibody Names Anti-Programmed Cell Death 1 Ligand 2 antibody
Anti-Pd-1 Ligand 2 antibody
Anti-Pd-L2 antibody
Anti-Pdcd1 Ligand 2 antibody
Anti-Programmed Death Ligand 2 antibody
Anti-Butyrophilin B7-Dc antibody
Anti-B7-Dc antibody
Anti-Cd Antigen Cd273 antibody
Anti-PDCD1LG2 antibody
Anti-B7DC antibody
Anti-CD273 antibody
Anti-PDCD1L2 antibody
Anti-PDL2 antibody

Information sourced from Uniprot.org

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