Anti-CD25 antibody (ECD) [ZM466] (STJ180671)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenRecombinant protein corresponding to the external domain of human interleukin-2 receptor protein
General Information
| Short Description | Mouse monoclonal CD25 (ECD) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZM466 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | IL2RA |
| Gene ID | 3559 |
| Uniprot ID | IL2RA_HUMAN |
| Immunogen | Recombinant protein corresponding to the external domain of human interleukin-2 receptor protein |
| Immunogen Region | ECD |
| Specificity | Positive Control: Tonsil or lymph node |
Additional Info
| Function | Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. |
| Protein Name | Interleukin-2 Receptor Subunit AlphaIl-2 Receptor Subunit AlphaIl-2-RaIl-2r Subunit AlphaIl2-RaTac AntigenP55Cd Antigen Cd25 |
| Database Links | Reactome: R-HSA-5673001Reactome: R-HSA-8877330Reactome: R-HSA-9020558Reactome: R-HSA-912526 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-2 Receptor Subunit Alpha antibodyAnti-Il-2 Receptor Subunit Alpha antibodyAnti-Il-2-Ra antibodyAnti-Il-2r Subunit Alpha antibodyAnti-Il2-Ra antibodyAnti-Tac Antigen antibodyAnti-P55 antibodyAnti-Cd Antigen Cd25 antibodyAnti-IL2RA antibody |
Information sourced from Uniprot.org