| Host: | Rat |
| Applications: | FC |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rat monoclonal antibody anti-Signal transducer CD24 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | M1/69 |
| Conjugation: | PE/Cyanine5 |
| Isotype: | IgG2bk |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Concentration: | 5 Mu L/Test |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Gene Symbol: | Cd24 |
| Gene ID: | 12484 |
| Uniprot ID: | CD24_MOUSE |
| Tissue Specificity | In lymphoid, myeloid, and erythroid cells. |
| Post Translational Modifications | The identity of the N- and O-linked polysaccharides is not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc. |
| Function | May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. |
| Protein Name | Signal Transducer Cd24 Lymphocyte Antigen 52 Ly-52 M1/69-J11d Heat Stable Antigen Hsa Nectadrin R13-Ag X62 Heat Stable Antigen Cd Antigen Cd24 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Antibody Names | Anti-Signal Transducer Cd24 antibody Anti-Lymphocyte Antigen 52 antibody Anti-Ly-52 antibody Anti-M1/69-J11d Heat Stable Antigen antibody Anti-Hsa antibody Anti-Nectadrin antibody Anti-R13-Ag antibody Anti-X62 Heat Stable Antigen antibody Anti-Cd Antigen Cd24 antibody Anti-Cd24 antibody Anti-Cd24a antibody Anti-Ly-52 antibody |
Information sourced from Uniprot.org