| Host: | Rat |
| Applications: | FC |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rat monoclonal antibody anti-Low affinity immunoglobulin epsilon Fc receptor is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | B3B4 |
| Conjugation: | FITC |
| Isotype: | IgG2ak |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
| Gene Symbol: | Fcer2 |
| Gene ID: | 14128 |
| Uniprot ID: | FCER2_MOUSE |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
| Protein Name | Low Affinity Immunoglobulin Epsilon Fc Receptor Fc-Epsilon-Rii Lymphocyte Ige Receptor Cd Antigen Cd23 |
| Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein Lipid-Anchor Secreted |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody Anti-Fc-Epsilon-Rii antibody Anti-Lymphocyte Ige Receptor antibody Anti-Cd Antigen Cd23 antibody Anti-Fcer2 antibody Anti-Fcer2a antibody |
Information sourced from Uniprot.org