Host: | Rat |
Applications: | FC |
Reactivity: | Mouse |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: | Rat monoclonal antibody anti-Low affinity immunoglobulin epsilon Fc receptor is suitable for use in Flow Cytometry research applications. |
Clonality: | Monoclonal |
Clone ID: | B3B4 |
Conjugation: | APC |
Isotype: | IgG2ak |
Formulation: | PBS with 0.05% Proclin300, 1% BSA |
Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Gene Symbol: | Fcer2 |
Gene ID: | 14128 |
Uniprot ID: | FCER2_MOUSE |
Post Translational Modifications | N- and O-glycosylated. |
Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
Protein Name | Low Affinity Immunoglobulin Epsilon Fc Receptor Fc-Epsilon-Rii Lymphocyte Ige Receptor Cd Antigen Cd23 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein Lipid-Anchor |
Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody Anti-Fc-Epsilon-Rii antibody Anti-Lymphocyte Ige Receptor antibody Anti-Cd Antigen Cd23 antibody Anti-Fcer2 antibody Anti-Fcer2a antibody |
Information sourced from Uniprot.org