Anti-CD21 antibody [IHC533] (STJA0042110)

SKU:
STJA0042110
£135.50 - £370.50
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Short Description :Mouse monoclonal anti-CD21 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-p
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :IHC533
Isotype:IgG2a
Conjugation:Unconjugated
Formulation:Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1 year. Do not freeze.
Specificity:Tested and validated on tonsil, lymph node tissue.
Background Cluster of Differentiation 21 (CD21) is a glycoprotein on the surface of B-cells that is bound by Epstein-Barr virus (EBV) during infection of these cells. CD21 staining is useful for recognizing follicular dendritic cell matrices in normal tonsillar and lymph tissue, and can also stain dendritic cell sarcomas. CD21 is also useful for distinguishing marginal zone lymphoma with follicular involvement from follicular lymphoma with marginal zone differentiation. When used in concert with other B-and T-cell markers, CD21 is valuable for differentiating between nodular lymphocyte-predominant Hodgkin s lymphoma, T-cell/histiocyte-rich B-cell lymphoma, and lymphocyte-rich classic Hodgkin s lymphoma. CD21 staining is useful for recognizing abnormal follicular dendritic cell patterns in angioimmunoblastic T-cell lymphoma and follicular T-cell lymphoma.

Information sourced from Uniprot.org