Anti-CD21 antibody [4C5] (STJ16100747)

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STJ16100747-1
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: IHC-F/IF/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-CD21 is suitable for use in Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 4C5
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: serum with 0.1% sodium azide
Concentration: 60 ug/mL
Dilution Range: IHC-F 1:20-1:50
IF
FC 1:50
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: fragments human tonsil
Background A BALB/c mouse was immunized subcutaneously in its footpads with fragments of a human tonsil. After fusing the lymphocytes from the popliteal lymph nodes of this mouse with murine SP2/0 myeloma cells, the antibody producing cells were selected on their immunohistochemical staining pattern. Later on the antibody was biochemically analysed and revealed to recognize the CD21 molecule (140kD) by immunoprecipitation procedures. This antibody reacts with the CD21 (140kD) molecule, expressed (moderate) on mature B-cells and (at high density) on follicular dendritic cells (FDC).

Information sourced from Uniprot.org

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