Anti-CD20/MS4A1 antibody (C-Term) (STJ70052)

SKU:
STJ70052-100
£312.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-CD20/MS4A1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:4000.
WB: Approx 35kDa band observed in Human Lymph lysates (calculated MW of 33.1kDa according to NP_068769.2). Recommended concentration: 0.003-0.01µg/ml. Primary incubation was 1 hour.
IHC
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: MS4A1
Gene ID: 931
Uniprot ID: CD20_HUMAN
Immunogen Region: C-Term
Accession Number: NP_068769.2; NP_690605.1
Specificity: Please note that both reported variants (NP_068769.2 and NP_690605.1) encode the same protein.
Immunogen Sequence: CQDQESSPIENDSSP
Post Translational Modifications Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate.
Function B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Protein Name B-Lymphocyte Antigen Cd20
B-Lymphocyte Surface Antigen B1
Bp35
Leukocyte Surface Antigen Leu-16
Membrane-Spanning 4-Domains Subfamily A Member 1
Cd Antigen Cd20
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lipid-Anchor
Constitutively Associated With Membrane Rafts
Alternative Antibody Names Anti-B-Lymphocyte Antigen Cd20 antibody
Anti-B-Lymphocyte Surface Antigen B1 antibody
Anti-Bp35 antibody
Anti-Leukocyte Surface Antigen Leu-16 antibody
Anti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibody
Anti-Cd Antigen Cd20 antibody
Anti-MS4A1 antibody
Anti-CD20 antibody

Information sourced from Uniprot.org