Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-T-cell surface glycoprotein CD1e, membrane-associated (321-370 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CD1E |
Gene ID: |
913 |
Uniprot ID: |
CD1E_HUMAN |
Immunogen Region: |
321-370 aa |
Specificity: |
CD1E Polyclonal Antibody detects endogenous levels of CD1E protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the C-terminal region of human CD1E at the amino acid range 321-370 |
Post Translational Modifications | Mono-ubiquitinated. Proteolytically cleaved in late endosomes to yield a soluble form. |
Function | T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. |
Protein Name | T-Cell Surface Glycoprotein Cd1e - Membrane-AssociatedHcd1eR2g1Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - SolubleScd1e |
Cellular Localisation | T-Cell Surface Glycoprotein Cd1eMembrane-Associated: Golgi Apparatus MembraneSingle-Pass Type I Membrane ProteinEarly EndosomeLate EndosomePredominantly Localized In The Trans-Golgi Network In Immature Dendritic CellsAnd As A CleavedSoluble Protein In The Lysosome Lumen Of Mature Dendritic CellsSoluble: Lysosome Lumen |
Alternative Antibody Names | Anti-T-Cell Surface Glycoprotein Cd1e - Membrane-Associated antibodyAnti-Hcd1e antibodyAnti-R2g1 antibodyAnti-Cd Antigen Cd1e Cleaved Into - T-Cell Surface Glycoprotein Cd1e - Soluble antibodyAnti-Scd1e antibodyAnti-CD1E antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance