| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD1B |
| Gene ID: | 910 |
| Uniprot ID: | CD1B_HUMAN |
| Immunogen Region: | 18-303 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human CD1B (NP_001755.1). |
| Immunogen Sequence: | SEHAFQGPTSFHVIQTSSFT NSTWAQTQGSGWLDDLQIHG WDSDSGTAIFLKPWSKGNFS DKEVAELEEIFRVYIFGFAR EVQDFAGDFQMKYPFEIQGI AGCELHSGGAIVSFLRGALG GLDFLSVKNASCVPSPEGGS RAQKFCALIIQYQGIMETVR ILLYETCPRYLLGVLNAGKA DLQRQVKPEAWLSSGPSPGP GRLQLVCHVSGFYPKPVWVM WMRGEQEQQGTQLGDILPN |
| Tissue Specificity | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. |
| Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
| Protein Name | T-Cell Surface Glycoprotein Cd1bCd Antigen Cd1b |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinEndosome MembraneLysosome MembraneSubject To Intracellular Trafficking Between The Cell MembraneEndosomes And Lysosomes |
| Alternative Antibody Names | Anti-T-Cell Surface Glycoprotein Cd1b antibodyAnti-Cd Antigen Cd1b antibodyAnti-CD1B antibody |
Information sourced from Uniprot.org
