• C57BL/6 murine splenocytes were stained with Anti-CD183/CXCR3 antibody (STJA0000683) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.

Anti-CD183/Cxcr3 antibody [CXCR3-173] {APC} (STJA0000683)

SKU:
STJA0000683

£166.50 - £261.50
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Host: Armenian Hamster
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Armenian Hamster monoclonal antibody anti-C-X-C chemokine receptor type 3 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: CXCR3-173
Conjugation: APC
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 1% BSA
Concentration: 0.2 mg/mL
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: Cxcr3
Gene ID: 12766
Uniprot ID: CXCR3_MOUSE
Tissue Specificity Expresses in lymphoid organs and Th1 cells.
Post Translational Modifications Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding. N-glycosylated.
Function Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21.
Protein Name C-X-C Chemokine Receptor Type 3
Cxc-R3
Cxcr-3
Interferon-Inducible Protein 10 Receptor
Ip-10 Receptor
Cd Antigen Cd183
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-X-C Chemokine Receptor Type 3 antibody
Anti-Cxc-R3 antibody
Anti-Cxcr-3 antibody
Anti-Interferon-Inducible Protein 10 Receptor antibody
Anti-Ip-10 Receptor antibody
Anti-Cd Antigen Cd183 antibody
Anti-Cxcr3 antibody
Anti-Cmkar3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance