Anti-CD182/CXCR2 nanobody [SAA1360] (STJN000177)

Anti-CD182/CXCR2 nanobody [SAA1360] (STJN000177)

SKU:
STJN000177
€473.13 - €2,040.63
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Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA/IF/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-C-X-C Chemokine Receptor Type 2 is suitable for use in ELISA, Immunofluorescence, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : SAA1360
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: CXCR2
Gene ID: 3579
Uniprot ID: CXCR2_HUMAN
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Protein Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Cdw128b
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Il-8 Receptor Type 2
Cd Antigen Cd182
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Nanobody Names Anti-C-X-C Chemokine Receptor Type 2 nanobody
Anti-Cxc-R2 nanobody
Anti-Cxcr-2 nanobody
Anti-Cdw128b nanobody
Anti-Gro/Mgsa Receptor nanobody
Anti-High Affinity Interleukin-8 Receptor B nanobody
Anti-Il-8r B nanobody
Anti-Il-8 Receptor Type 2 nanobody
Anti-Cd Antigen Cd182 nanobody
Anti-CXCR2 nanobody
Anti-IL8RB nanobody

Information sourced from Uniprot.org

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