Anti-CD18 antibody [CLB-LFA-1/1] {FITC} (STJ16101399)

SKU:
STJ16101399-05

£568.50
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Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD18 is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: CLB-LFA-1/1
Conjugation: FITC
Formulation: PBS with BSA and 0.1% sodium azide
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Human CD18
Background CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes. CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling. CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1) , alphaMbeta2 (CD11b/CD18, Mac-1, CR3) , alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance