| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sialomucin core protein 24 (110-190 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CD164 |
| Gene ID: |
8763 |
| Uniprot ID: |
MUC24_HUMAN |
| Immunogen Region: |
110-190 aa |
| Specificity: |
CD164 Polyclonal Antibody detects endogenous levels of CD164 protein. |
| Immunogen: |
Synthesized peptide derived from CD164 at the amino acid range 110-190 |
| Post Translational Modifications | Highly N- and O-glycosylated.contains sialic acid. The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain. |
| Function | Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. |
| Protein Name | Sialomucin Core Protein 24Muc-24EndolynMulti-Glycosylated Core Protein 24Mgc-24Mgc-24vCd Antigen Cd164 |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane ProteinEndosome MembraneCell MembraneIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Sialomucin Core Protein 24 antibodyAnti-Muc-24 antibodyAnti-Endolyn antibodyAnti-Multi-Glycosylated Core Protein 24 antibodyAnti-Mgc-24 antibodyAnti-Mgc-24v antibodyAnti-Cd Antigen Cd164 antibodyAnti-CD164 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
