Anti-CD16 antibody [LNK16] (STJ16100960)

Anti-CD16 antibody [LNK16] (STJ16100960)

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STJ16100960-100
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Non-Human Primates/Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-CD16 is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : LNK16
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Purification: Purified by protein-A affinity chromatography.
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Normal human peripheral blood granulocytes
Background CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms – FcgammaRIII-A and-B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Information sourced from Uniprot.org

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